Pre-Workout Ingredient Showdown (WHICH WORKS BEST?) – ATHLEAN-X™

by YouTube Team

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Pre-workout supplements are among the top three most used supplements by those that work out and take their training seriously. In this video, I’m going to show you the best pre-workout ingredients and which you should be looking for if you are going to look to benefit from a supplement prior to training.

This battle pits L-Arginine vs. Citrulline Malate as to which is the better pre workout supplement ingredient. Both of these are chosen for their ability to provide muscle pumps during training, with the Citrulline Malate giving you the additional benefit of improved muscular endurance and power. When it comes to the pump however, it is important to first understand that this is not a totally benign effect meant to feed your ego while you train.

The muscle pump has the effect of delivering more blood and water to the working muscles, allowing them to train harder by helping to keep them hydrated while removing muscle waste product more efficiently. That said, the way these ingredients work is through their effect on nitric oxide.

Nitric oxide has a vasodilation effect on your arterial walls that are feeding your skeletal muscles. When the nitric oxide relaxes the arteries you get increased flow of blood to the working muscles and the pump is increased.

That said, arginine has a significant problem when it comes to effectively leading to the production of nitric oxide and that is that when taken orally it becomes subject to much more breakdown than citrulline malate. L-Arginine is not efficiently converted to nitric oxide because it becomes susceptible to the arginase enzyme in the digestive tract and liver. This leaves you with far less assimilation of the original arginine that you thought you were taking. This can happen at up to a 70-99% percent loss depending on other health factors like cholesterol levels.

On the other hand, citrulline bypasses the gut and liver and converts much more readily to arginine. From here it can be converted to nitric oxide at a much more efficient clip. In fact, many studies suggest that you can get up to a 300% higher net absorption of nitric oxide via this pathway than the previous.

Additionally, the citrulline in it’s citrulline malate form is even more beneficial because it provides additional energy for better muscle endurance. The malic acid bound to the L-Citrulline feeds the Krebs Cycle which lets you produce more cellular ATP (the metabolic currency of energy).

For a pre-workout backed by sports science with no proprietary blends, be sure to use what the pros use and head to to get the ATHLEAN-Rx supplements. Our pre-workout, post-workout, muscle recovery stack is the one counted on by serious lifters to maximize the gains they see from their hard training.

For more supplement videos covering pre workout reviews, post workouts and supplements to help you build muscle, be sure to subscribe to our channel here on youtube at

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25 comments

painmymiddlename August 12, 2020 - 10:49 pm

Anyone taking l norveline? I heard it works very well but it might do damage to the brain. Is it ok to take small doses for short period of time?

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basha mohammed August 26, 2020 - 9:45 am

I'm using Acetyl L-Carnitine as pre-workout suppliment. I'm working out in fasted state in the morning. I'm looking to shred some fat around my belly. Can I combine Citrulline Malate with L-Carnitine b4 workout?

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Metalforlife007 September 20, 2020 - 4:51 am

3 shots of jack Daniel's 15-20 minutes before workout will do the work

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Rod Bowles October 11, 2020 - 8:58 pm

Should make mention that acetylcholine starts the whole process. So you should take a form of choline in your preworkout

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Mario October 17, 2020 - 10:23 pm

If I only take l-citrulline malate with 6 to 8 g per day, I don't need to take l-arginine too? I am 58 years old and I do bodybuilding

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D Z November 28, 2020 - 3:14 pm

Can you make a video on SARM?

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Mr. Pete Channel is 100 away 2 the big time! December 5, 2020 - 6:39 am

Feed Me More's "Wake Up!" brand pre workout haves both Citruline Malate & Arginine. Guess they were like "Which should we use?" and they be like "Guess what? F*** it! Put in both!"

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Nesar Siddiqui December 17, 2020 - 6:37 pm

Much appreciate this Jeff. Great explanation

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Mazzer B January 21, 2021 - 6:15 pm

Really informative vid I take combo of this with l-lysine and l-ornithine xx

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Danielle Losonczy February 1, 2021 - 3:07 am

How long does it take for your blood vessels to dilate

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Adrian Rusu February 6, 2021 - 9:56 am

6g of citrulin a day?

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Jose Perez February 6, 2021 - 8:45 pm

Good info! BUT PLEASE SLOW DOWN!!!!!!

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Complete Tune February 12, 2021 - 9:37 am

Once again proving that Jeff has zero idea how the two work on the body and why . Keep your day job stud. You have zero idea what the hell your talking about . Your Google education failed you again.

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Markus Inks March 16, 2021 - 11:44 pm

BSN N. O. XPLODE IS MY FAVORITE PREWORKOUT!!!! PLEASE COMMENT.,…. THANKS MARKUS

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Tony P March 20, 2021 - 9:52 pm

I’ve been using the l-Arginine and citrulline Malate together and I can feel a whole difference and my workouts are way better. I love it. I think it’s worth it.

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Isaac Clark April 25, 2021 - 4:03 am

Both?

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Eduardo Oliva May 24, 2021 - 9:41 pm

@ATHLEAN-X what’s the best form liquid, powder, or tablet? 6 to 8 grams, right??

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Miguel Rodriguez June 15, 2021 - 7:12 am

Snort it?

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D H June 17, 2021 - 2:27 pm

How much L- citralline is equal to 2g of arginine?

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rubber duky July 2, 2021 - 1:20 am

You also have to remember when you're having vasodilation, even Russell the love muscle is getting benefits from this. Taking one to one and a half hours before hanky panky, ……yeah…

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Stefan Weilhartner August 20, 2021 - 8:58 pm

yes. citrulin malate, got it. but what about aakg, does it survive going through the liver or is it just marketing blabla?

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sda123 August 23, 2021 - 4:35 pm

take both

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rgaufman August 24, 2021 - 11:44 am

Has anything changed in the past 5 years or is this still up to date?

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Matt Sobota September 2, 2021 - 2:51 am

Would you still recommend it to those with low blood pressure?

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C D September 15, 2021 - 8:35 pm

I love you, dad. Uh I mean Jeff.

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