Muscle Memory Explained (WITH STICK FIGURES!) – ATHLEAN-X™

by YouTube Team

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You have likely heard the term muscle memory, but do you really know what it means and what its implications are for your training and workouts? In this video, I’m going to show you how the process of muscle memory exists and why it should ease your mind when you are forced to take some time away from the gym due to illness, family issues, injury or any other reason. No, you won’t lose all your hard earned gains long term. In fact, you might even benefit from the layoff.

You see, as you build new muscle tissue, the muscle fibers grow in size. That said, they ultimately reach a growth potential limit that is driven by the regulators of the fiber size called the myonuclei. These cellular powerhouses are contributed to a growing muscle fiber by the satellite cells that surround the fibers and ultimately bind to it as the result of muscle stress and inflammation (ie. after a particularly hard training session).

Once recruited, these myonuclei tend to stick around for awhile, a long while! Even though the fiber itself may shrink in size due to the inactivity caused by a layoff from your workouts, the myonuclei stay in the same number. This is important because they are ultimately determining the size of the fiber’s growth. With a limited capacity of growth (called the myonuclear domain), the only way to increase a fiber’s size is to ultimately recruit more myonuclei.

The best way to do this is to stress a muscle (either through increased tension, metabolic stress, or increased training frequency) which results in an inflammatory process that kick starts the recruitment of the satellite cells to the fiber. This will lead to a donation of the myonuclei which will set the stage for increased protein synthesis and long term growth.

When you have to lay off the weights because of an injury or illness, you see that you do lose muscle size. That is normal and to be expected. Why? Because your body does not want to try and support that extra tissue metabolically, especially because it is not functionally beneficial while the priority is to fight off an infection or bug. That said, while the fibers may shrink the myonuclei and ultimately the size of the fiber they can support are unaffected or unchanged.

When you get back to your hard workouts, you bounce back fast and your size returns quickly. This is the same reason why taking a forced break from your training every now and then can help to not only reinvigorate your enthusiasm for training but also give your body a chance to recover and grow.

For a complete training program that blends the perfect amount of hard training with much needed recovery, be sure to head to and get the ATHLEAN-X Training System. Start training like an athlete and see just how quickly you can make gains in size, strength and performance with the leading sports physical therapist guiding your every workout.

For more videos on how to overcome overtraining and use muscle memory as a valuable tool for preserving your hard earned muscle gains long term, be sure to subscribe to our channel here on youtube at

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36 comments

Whatsupmududes Yeet November 21, 2019 - 1:29 am

Instructions unclear now have 4 black labs and a Jesse

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Chetan Dhar November 24, 2019 - 11:20 am

My last workout was about the time this video came out. How many dogs do I have now?

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Arup Ghosh November 25, 2019 - 2:20 am

Sir, I'm having a minor shoulder impeachment. Can u tell me how long will it take to recover? I'm loosing hope and getting demotivated. 😣

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Anders Berg November 25, 2019 - 5:59 pm

Just had the flu for 10 days. Thought all my (hard-gainer) gains were gone. Now i know better. Thank you!

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James Woodall November 26, 2019 - 3:08 pm

?So muscle memory and nuclei overload is the same ?

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1STMAN December 28, 2019 - 5:53 pm

Chael Sonnens long lost Brother

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Leon Kabo January 7, 2020 - 1:00 pm

This is encouraging, i stopped training because i was recovering from a surgery for 2 months, i lost a lot of hard earned muscle mass..

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Van Brown January 21, 2020 - 9:22 pm

thank you bro you are greatly appreciated

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Christian MacIntyre January 26, 2020 - 6:59 am

0:57 because Jeff is so damn fast and athletic he could easily catch the dogs, even if they went in different directions

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Daniel tolksdorf March 20, 2020 - 9:30 pm

Can i do that on a caloric deficit?

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ERICZONg1 March 24, 2020 - 11:27 am

coronavirus crew coming in !

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Luis Ernesto Ochoa Valle March 31, 2020 - 2:42 am

Who else is here due to coronavirus because you thought you would lose muscle and gyms are closed?

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Autentyczny Trener April 3, 2020 - 2:18 pm

I know you wrote this a while ago but can I see some kind of article that says how the satellite cells donate their myonuclei ? I can't find anything online, thx

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Kam April 10, 2020 - 11:40 am

It’s corona time

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skeetuschrist May 3, 2020 - 4:44 pm

Thanks braaah

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Vinzent May 15, 2020 - 11:58 pm

I'm looking foward to experience the muscle memory effect as soon as the gyms reopen after quarantine

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Exotica May 27, 2020 - 8:59 pm

Corona virus brought me here.

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Frankystrings July 3, 2020 - 2:40 am

3:02 legendary

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450 July 4, 2020 - 12:56 am

3:03 i don't know why but i laughed so loud

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P.P July 26, 2020 - 5:33 pm

What's a "long time"?

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Adnaan Fakir September 14, 2020 - 10:41 am

More stress will get you more dogs in your fibers.

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Music and poems October 23, 2020 - 6:38 am

I think I won't gain again …so depressed… didn't train for 6 months 😭 ….now training since 10 days and still didn't gained any muscles

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Slobo November 20, 2020 - 3:14 am

11m subs well deserved.. Jeffs the best.. Day 1 back in the gym

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Lala A January 23, 2021 - 8:20 pm

he foresaw the pandemic

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Rob Andera March 7, 2021 - 4:06 pm

Glad I found this I truly thought I was screwed but no more excuses time to ri it up
"LOVE IT,
KILL IT"
~Rich Piana~

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MADEN LAUR March 21, 2021 - 2:27 pm

1:09 why does it looks like someones belly😂 and some food it😂😂

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Sky Cloud March 24, 2021 - 9:56 am

Quite reassuring really as I tend to get more anxious missing a few workouts here and there.

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Eli Delano April 8, 2021 - 9:15 pm

6:06 and that is the definition of insanity

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Brandon Rodriguez April 15, 2021 - 5:21 pm

Lmao im here because i couldn't workout due to the pandemic

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Justin April 23, 2021 - 10:51 pm

I quit lifting for almost 6 years. Then went back into the gym and got my gains back within a couple months. Even within a few weeks people thought I drank some magic potion to get big real quick. Nope, it's just that muscle memory. So I can attest to this science from personal experience.

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Mr J June 15, 2021 - 4:36 pm

Great explanation

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HUJAMBO Korodani July 11, 2021 - 5:02 am

real talk !

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Simon Wikberg October 8, 2021 - 11:32 pm

This video made me a bit releifed. I used to train allot when I was 18-23 but then quit. And every time I tried to start to go to gym I just felt shit since I was so much weaker than I was. I will try to stick with it longer this time around at 29. Lets see how long it takes to lift 110kg in bench and 230kg Deadlift. I dont even know if I can bench 75kg now.

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Brianna Chamberlain December 2, 2021 - 5:48 am

Would if I took 5 years off or more?

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Kevin C.A. Schneider December 15, 2021 - 10:42 am

Ive been training since 10 years straight, took one year off because i got sick, now im back and in just 1 month i made incredible gains again im still pretty weak but the volume is coming back very, very fast. Hard work pays off.

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MurderousJohnny January 2, 2022 - 2:14 am

have seriously workout in almost 9 years, I hope this is true. not starting scratch is helping the motivation.

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